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The Porcine Reproductive and Respiratory Syndrome (PRRS) is an economically significant disease that affects the pig industry globally. This section reviews the latest new features on this disease.
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PRRSV pathology in the lungs

Lungs of a piglet exterminated 14 days PI, inoculated with higly pathogenic Type I subtype 3 strain Lena

The tissue damage is the consequence of direct apoptosis (and necrosis) of alveolar macrophage and their neighboring cells due to the release of apoptotigenic cytokines, reactive oxygen species, and nitric oxide.

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PRRSV in Europe: where did it come from?

PRRSV diversity in Europe

The great genetic diversity of East European strains has practical implications, the sensitivity of some of the diagnostic PCR methods can be compromised and the efficacy of the current PRRSV vaccines against the East European genetic variants still needs to be elucidated.

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