Only a few EU countries are discussing national eradication as a possibility.
The Porcine Reproductive and Respiratory Syndrome (PRRS) is an economically significant disease that affects the pig industry globally. This section reviews the latest new features on this disease.
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The tissue damage is the consequence of direct apoptosis (and necrosis) of alveolar macrophage and their neighboring cells due to the release of apoptotigenic cytokines, reactive oxygen species, and nitric oxide.
Currently, no single RT-PCR assay could be recommended as a universal method allowing for detection of all PRRSV strains with optimal sensitivity.
In Korea, it is common to vaccinate sows as a whole-herd mass vaccination program, where all sows are vaccinated quarterly with a type 2 PRRSV vaccine. Therefore, it is recommended to vaccinate breeding females quarterly with additional type 1 PRRSV vaccine to control type 1 PRRSV infection.
Type 1 PRRSV is highly prevalent in Korean swine herds and currently reproductive failure is more important consequence of infection with type 1 PRRSV, than is respiratory diseases in growing pigs.
According to the present status and the experiences obtained during the previous one and a half year, Hungary will get free of PRRS by 2020.
The great genetic diversity of East European strains has practical implications, the sensitivity of some of the diagnostic PCR methods can be compromised and the efficacy of the current PRRSV vaccines against the East European genetic variants still needs to be elucidated.