Is the right strategy to get a farm stable, that is, control clinical signs reducing the economic impact of the disease; or should a farm adopt strategies to go “negative”? As for other questions in the epidemiological field, our answer is “it depends”.
One of the challenges when conducting a disease elimination project is to ensure that the pathogen has in deed been eliminated from the herd.
In general terms, immunization through vaccination is the easiest and safest way to stabilize a herd.
PRRSV by itself may induce mild-to-severe respiratory disease but rarely results in mortality.
Resolving the basis of viral and host variation will require identification and characterization of key B- and T-cell epitopes conserved among diverse PRRSV, and of the molecular and structural details of key effector antibodies, T-cell antigen receptors, and MHC molecules that mediate broad, cross-protective immunity.
The total cost of productivity losses to US producers is estimated at US$664 million annually but productivity losses are shifting from the growing pig herd to the sow herd.