Genomic changes can be associated with increased virulence or decreased immunogenicity.
Porcine circovirus (PCV2)
The PCV2 has been associated, in an ongoing way and throughout time, with more pathologies called, collectively, diseases associated with the PCV2 (PCVDs): PCV2 systemic disease, PCV2 lung disease, PCV2 enteric disease, PCV2 reproductive disease,PCV2 subclinical infection and porcine dermatitis and nephropaty syndrome.
Novelties about the excretion routes, the transmission routes, the risk factors, etc., and explanation about how the PCV2 becomes a pathogenic virus.
The most effective way of avoiding the production losses associated with the PCV2 consists in avoiding the appearance of the viraemia by inducing a passive or an active immunity that minimizes the circulation of the virus in the farm.
A summary of current knowledge to address frequently asked questions from producers and practitioners on PCV2-associated reproductive disease.
Given the high prevalence of the infection due to the PCV2 and its presence in healthy and sick animals, the serological tests against this pathogen have been questioned as a diagnostic test.
Available data indicate that PCV2 has the ability to modulate the immune response, not only during the obvious overt disease but also in a subclinically infection.