Abstracts - Pig health

Pigs in this study appeared to respond very similarly between the IN and IM routes at the time of processing when boosted at weaning by the IM route.

This is the first report to 1) identify a novel porcine pestivirus associated with CT and 2) successfully reproduce CT following inoculation of fetuses in utero.

The estimated impact of PCV-2 vaccination revealed a highly significant decline in total antimicrobial drug use on finishing farms.

Intervention strategies targeting sows would likely have a beneficial effect in reducing the occurrence of antimicrobial resistance in primary pig production.

Vesicular disease was experimentally induced in nursery-age pigs inoculated with SVA demonstrating for the first time a causal relationship between SVA infection and disease.

The results of the present study indicate that vaccination of pigs against erysipelas in the presence of antibiotics may result in a decrease or enhancement in the production of specific antibodies.

The study demonstrated that naive cattle, goats and pigs, in addition to antibody positive sheep, can be infected by HoBi-like virus via persistently infected calf and potentially transmit the virus.

Since the introduction of PCV2 vaccines in 2006, viral presence and viral loads have greatly decreased, and a genotypic shift dominated by PCV2b has occurred.

Under the conditions of this study, it makes no difference to protection whether PCV2 and PRRSV vaccines are administered concurrently. Concurrent vaccination is efficacious for controlling co-infection with PCV2 and PRRSV.

To increase efficiency, active sampling should be intensified (more animals sampled) and monitored fattening groups abandoned. This would significantly improve sensitivity and time to detection at comparable or lower costs.

This is the first case report in the United States associating SV-A with a clinical course of severe but transient neonatal morbidity and mortality followed by vesicular lesions in breeding stock animals.

Serum antibodies against NP provide an ideal universal diagnostic screening target and could provide a cost-effective approach for the detection and surveillance of IAV infections in swine populations.

The presence of isolates with epf gene variation with higher molecular weight also appears to be a characteristic of Brazilian S. suis serotype 2.

This study aimed at assessing possible associations between the biosecurity level, antimicrobial usage and farm and production characteristics in order to advice on best practices for a low antimicrobial usage and maximum animal health and production.

The reason for the variability of resistance between animal species is unknown and requires further research.  

Detection of SVA in mice and housefly samples and recovery of viable virus from mouse feces and small intestine here, suggests that these pests may play a role on the epidemiology of SVA.

The U.S. PEDV prototype and the S-INDEL-variant strains induced similar viremia levels in inoculated pigs.

This system may be useful for monitoring sentinel herds in real time, considerably reducing the financial and logistical costs of periodic sampling and increasing the chances of early detection of infection.

We describe here the construction of a novel vaccine strain that confers excellent protection against B. suis in a mouse model of infection.

Results demonstrated remarkable IAV diversity, and the complex, rapid and dynamic evolution of IAV during infection of vaccinated pigs that can only be appreciated with repeated sampling of individual animals and deep sequence analysis.

Our data indicates that although high titers of vaccine-derived MDA reduced homologous virus infection, transmission, and disease, MDA alone was sufficient to induce vaccine associated enhanced respiratory disease upon heterologous infection.

The attenuated S. Typhimurium BBS 866 strain, containing mutations in rfaH and multiple sRNAs, addresses the limitations of current Salmonella vaccines by providing cross-protection against Salmonella serovars in swine without interfering with established monitoring programs for Salmonella surveillance.

The IR method ascertains whether piglets are receiving adequate maternal antibodies until their own immune systems are developed.

These results showed that the highest assurance of providing PRRSV-negative semen to sow farms should be based on rRT-PCR testing of serum collected at the time of semen collection.