articles about immunity

Maternally derived immunity on immune responses elicited by piglet early vaccination: examples from respiratory and systemic pathogens

Depending on the levels of maternal derived immunity, a potential interference of vaccine intake may happen, jeopardizing vaccine seroconversion and efficacy.

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NutritionArticle

The role of vitamins in the piglet immune response

Are we forgetting the importance of vitamin levels in the post-weaning diet in the post-zinc oxide era?

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Figure 3.  An additional cost of a long-term alert is the deterioration of appetite and, consequently, a prolonged fattening period. Since the pressure from environmental stressors affects individual animals differently, there will be a differentiation in the weight of weaners or fattening pigs of the same age. Weight differentiation among animals of the same age may have serious economic consequences. Also, especially in young animals, a diet that does not contain nutrients essential for strengthening the anti-infectious resistance may make the animals more vulnerable to infection.

HealthArticle

Impact of stress on immune function, health, and productivity (2/2)

We conclude this two-part series by Professor Pejsak by examining how immune stress affects the pig's body, gut, and production.

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Figure 2. Minutes or hours after stress occurs, the hypothalamic–pituitary–adrenal (HPA) axis is activated. Pituitary gland secretes corticotrophin, which, reaching the adrenal cortex, causes the secretion of glucocorticoids, including cortisol. Glucocorticoids inhibit the activity of the pituitary and hypothalamus, thanks to which they regulate the intensity of the stress response. Cortisol has been widely used as a marker of stress in swine, also as a noninvasive test from saliva.

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HealthArticle

Impact of stress on immune function, health, and productivity (1/2)

What exactly goes on in a pig's body when exposed to acute or chronic stress? What implications does stress have on production? Professor Pejsak draws on decades of research to answer to explain.

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NutritionArticle

Intestinal microbiota of pigs determines the response to vaccines

Bacteria in the gut microbiota that stimulate the immune response to vaccines in pigs also stimulate growth.

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HealthAbstract

T-cell epitope content comparison (EpiCC) of swine H1 influenza A virus hemagglutinin

EpiCC thresholds can be evaluated for predictive accuracy of protection in future efficacy studies.

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HealthAbstract

Rotavirus C: prevalence in suckling piglets and the influence of maternal immunity on disease development

Insufficient lactogenic protection provided by gilts plays a key role in the development of and the increased prevalence of clinical rotavirus C disease.

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Figure 1: Ciliated pseudostratified epithelium with goblet cells, characteristic of the respiratory system.

HealthArticle

The pig's respiratory system and its defense mechanisms

What kind of cells make up the respiratory defense system of pigs? How do they organize and communicate with each other?

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HealthAbstract

A neutralizing monoclonal antibody-based competitive ELISA for CSF C-strain post–vaccination monitoring

The novel cELISA demonstrated excellent agreement and high level correlation with VNT. It is a reliable tool for sero-monitoring of C-strain vaccination campaign.

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Dr Kevin Waldron, Principal Research Fellow based in the Faculty of Medical Sciences at Newcastle University, UK.

NutritionPress releases

Process of nutritional immunity presented for the first time to animal nutritionists at Animine Academy

To limit bacterial growth, hosts have evolved mechanisms to sequester metals in a process termed ‘‘nutritional immunity”.

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NutritionAbstract

Dietary supplement of 25-hydroxyvitamin D3 in weaned piglets

High doses of 25(OH)D3 may improve immune functions and the antioxidant capacity in weaned pigs.

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HealthPress releases

A revival for comparative and veterinary immunology

Under the leadership of Pirbright’s Dr Elma Tchilian the Comparative and Veterinary Immunology Group (CVIG) has been revived and is actively engaging in opportunities to showcase the research of its members and bring knowledge of comparative and veterinary immunology to a wider audience.

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NutritionAbstract