The skin is the first defensive line, as is the largest organ of the body.
Immunology Research Unit
University of Parma. Italy
Research unit of Experimental and Clinical Immunology, Department of Veterinary Science – University of Parma
Prof. Paolo Martelli – DVM – Diplomate ECPHM - Full Professor
Prof. Paolo Borghetti – DVM- PhD – Diplomate ECPHM – Full Professor
Dr. Roberta Saleri – DVM – PhD
Dr. Benedetta Passeri – DVM- PhD
Dr. Elena De Angelis – Biologist – PhD
Dr Luca Ferrari – Biotechnologist – PhD
Dr. Elena Canelli – DVM – PhD – MS Molecular Virology – Resident ECPHM
Dr. Alessia Catella – DVM – PhD student
Dr. Giulia Ogno – Biotechnologist – PhD student
Dr. Valeria Cavalli – Biologist
The research activity is focused on the immune response in both experimental and field trials. Moreover, in vitro immune models and new innovative vaccines and route of administration are also under investigation.
Updated CV 13-Mar-2017
Mucosal surfaces, constantly exposed to foreign antigens, have developed the ability to protect the host from potentially harmful organisms by means of innate and acquired immune responses.
In the primary humoral immune response, a single class IgM in monomeric form is initially secreted. The secondary response induced by a subsequent exposure to the same antigen will be mainly characterized by the production of IgG isotype but at higher titre and affinity.
Specific humoral immunity is mediated by glycoproteins called antibodies or immunoglobulins.
The main mechanism of defense against intracellular infections, particularly virus.
The role of each player in the innate immunity response: Type 1 Interferons and pro-inflammatory cytokines, complement, acute phase proteins, antimicrobial proteins, phagocytes, NK cells, γ/δ T lymphocytes,...
Recognition of the pathogen is the first step of defensive immune response; both innate and specific immunity have mechanism to recognize the pathogen.
What the cytokines are, what they do and how they work on the immune system.