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Humoral response and colostral antibody transfer following 'one-dose' pre-mating vaccination of sows against porcine circovirus type-2

One-dose vaccination of sows against PCV2 induces colostral antibody transfer.

9 April 2014
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A study from CReSA investigated the presence of porcine circovirus type 2 (PCV2) DNA and antibody to the virus in the serum and colostrum of sows vaccinated prior to mating and in their offspring.

During the investigation, a total of 77 sows were randomly distributed into vaccinated (V, n=36) and non-vaccinated (NV, n=41) groups. One week before mating, sows were given a PCV2 vaccine (V group) or PBS (NV group) IM. Blood samples were taken from the sows at fixed time-points and colostrum samples were taken at farrowing. Blood samples were also taken from the piglets of the sows at 4 weeks of age.

The study revealed that immunisation of sows with one dose of commercial PCV2 vaccine prior to mating induces a robust humoral response that results in the provision of high concentrations of homogeneous colostral antibody.

Sibila M, Fraile L, Ticó G, López-Soria S, Nofrarías M, Huerta E, Llorens A, López-Jiménez R, Pérez D, Segalés J. Humoral response and colostral antibody transfer following 'one-dose' pre-mating vaccination of sows against porcine circovirus type-2. Vet J. 2013 Sep;197(3):881-3.

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