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Novel porcine sapelovirus found during SHIC-funded diagnostic investigation

Porcine sapelovirus has been implicated in an acute outbreak of atypical neurologic disease.

5 September 2016
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Using funds from Swine Health Information Center (SHIC)’s Support for Diagnostic Fees program, porcine sapelovirus has been implicated in an acute outbreak of atypical neurologic disease. Dr. Paulo Arruda, Iowa State University, led a team of diagnosticians (Dr. Kent Schwartz, ISU; Dr. Albert Rovira, UMN; Dr. Jerome Nietfeld, KSU) and research assistant professor Dr. Ben Hause, KSU, through the case, acting on the request of the submitting veterinarian and owner.

The initial and final case reports detailing the discovery of porcine sapelovirus, including videos of the clinically affected pigs, are posted on http://www.swinehealth.org/sapelovirus.

To date, sapelovirus from other species have not been reported to be associated with nervous disease. In this case, a novel sapelovirus was the only agent detected associated with a unique clinical presentation of CNS disease. At least one previous case report documents the neuroinvasive potential of porcine sapelovirus in swine. However, knowledge gaps remain in disease causation (i.e. Koch’s postulates as yet unfulfilled), epidemiology, pathogenesis and biologic relevance of this potential pathogen.

Wednesday July 27, 2016/ SHIC/ United States.
http://www.swinehealth.org

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