Read this article in:

Detection and characterization of an H4N6 avian-lineage Influenza A virus in pigs in USA

In late 2015, an avian-origin H4N6 influenza A virus was isolated from pigs in the United States.

Friday 1 December 2017 (2 years 14 days ago)

H4Nx viruses were reported in swine in Canada and China, but had not been recognized in swine in the USA. In late 2015, an avian-origin H4N6 influenza A virus was isolated from pigs in the United States during a routine diagnostic investigation of clinical respiratory disease in the herd.

Serological analysis from additional pigs at the farm and other pigs within the swine production system indicated that the virus did not efficiently transmit from pig-to-pig and the mode of transmission to swine could not be determined. The isolate was characterized at the molecular level and the pathogenesis and transmission was experimentally evaluated in pigs. Although the virus replicated in the lungs of pigs and caused mild pulmonary lesions, there was no evidence of replication in the upper respiratory tract or transmission to indirect contacts, supporting the findings on the farm.

Eugenio J. Abente, Phillip C. Gaugeb, Rasna R. Walia, Daniela S. Rajao, Jianqiang Zhang, Karen M. Harmon, Mary Lea Killian, Amy L. Vincent; Detection and Characterization of an H4N6 Avian-Lineage Influenza A Virus in Pigs in the Midwestern United States; Virology 511 (2017) 56-65

Article Comments

This area is not intended to be a place to consult authors about their articles, but rather a place for open discussion among users.
Leave a new Comment

Access restricted to 333 users. In order to post a comment you must be logged in.

Not a registered user of 333?sign upand access swine prices, the search engine, ...
It is fast and free
Are you registered in 333?LOGINIf you've forgotten your password we'll send it to you here