Experimental Mhyo and PCV2 co-inoculations have resulted in somewhat divergent results.
CReSA - UAB. Spain
Joaquim Segalés i Coma was born in Vic (Barcelona) in 1968, he graduated at the Veterinary Faculty of the Universitat Autónoma de Barcelona (UAB) in 1991. He then received a doctorate in Veterinary Science in 1996 at the same university after having spent 15 months at the University of Minnesota (UM) in the USA, under the codirectorship of Dr. Mariano Domingo (UAB) and Dr. Carlos Pijoan (UM). In 2000 he achieved a diploma at the European College of Veterinary Pathology (ECVP). In year 2004 he graduated at the European College of Porcine Health and Management (ECPHM), of which he is a founding member and its current vice-president. He currently works as professor at the Department of Animal Anatomy and Welfare at the Veterinary Faculty of the UAB, where he teaches in the area of pathologic anatomy and porcine clinic. He is also the Director of the Centre de Recerca en Sanitat Animal (CReSA).
Dr. Segalés has taken part in numerous research projects, at both a national and a European level. He is especially skilled in different porcine diseases and has collaboration agreements with different enterprises, both national and European, that are involved in the sector. Of the many lines of research that he has participated in, the most important are the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), Haemophilus parasuis, the Aujeszky Disease Virus (ADV), the Hepatitis E Virus (HEV), torque teno sus virus and diseases associated with Porcine Circovirus type 2 (PCV2). It is also worth mentioning that Dr. Segalés participated in the first identification in Spain of the Post-weaning Multi-System Wasting Syndrome or Porcine Circovirus in 1997 and of the Porcine Dermatitis and Nephropathy Syndrome in 1996. As a result of these investigations he is the co-author of more than 200 articles published in international scientific journals, as well as being co-author of ten chapters of books with international prestige of which perhaps the most important is Porcine circovirus diseases in the 9th and 10th edition of the book Diseases of Swine. He is also the co-author of a book on swine livestock necropsy as well as three books on clinical cases in swine.
Updated CV 14-May-2013
The PCV2 has been associated, in an ongoing way and throughout time, with more pathologies called, collectively, diseases associated with the PCV2 (PCVDs): PCV2 systemic disease, PCV2 lung disease, PCV2 enteric disease, PCV2 reproductive disease,PCV2 subclinical infection and porcine dermatitis and nephropaty syndrome.
Novelties about the excretion routes, the transmission routes, the risk factors, etc., and explanation about how the PCV2 becomes a pathogenic virus.
The most effective way of avoiding the production losses associated with the PCV2 consists in avoiding the appearance of the viraemia by inducing a passive or an active immunity that minimizes the circulation of the virus in the farm.
Available data indicate that PCV2 has the ability to modulate the immune response, not only during the obvious overt disease but also in a subclinically infection.
One issue is to overcome maternal immunity, which is true for all PCV2 vaccines in the market, and another is whether the most from these vaccines is achieved independently of the PCV2 antibody titre at vaccination
We may have some highly efficient vaccines, but we shouldn’t forget that for their application we must obtain good diagnostic information, and that in all cases we should not lose sight of good management and a good control of the concomitant diseases.
Between 1995 and 1997, at the beginning of an epizootic called “maladie de l’amagrissement du porcelet” (MAP), it was observed that the farms that were most affected and that had the most losses, generally presented obvious deviations from what we would consider to be a suitable management of the animals and facilities. This is why Dr. François Madec made a list of management practices with the aim of improving the anomalous situation observed.