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Spain: vaccine against foot and mouth disease - a successful case of technology transfer

An innovative approach that combines multiple copies of the structural components (called epitopes) of the viruses that generate protective immunity in a single molecular platform.

Wednesday 30 October 2013 (4 years 9 months 17 days ago)
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The vaccine is the result of a collaborative project between UPF, the Spanish Higher Council for Scientific Research (CSIC), the Spanish National Institute for Agricultural and Food Research and Technology (INIA) and Genome España (now known as the Spanish Foundation for Science and Technology - FECYT).

The vaccine, designed and produced on a pilot scale in the protein chemistry laboratory at UPF, is an innovative approach that combines multiple copies of the structural components (called epitopes) of the viruses that generate protective immunity in a single molecular platform.

It basically consists of peptides, and is produced by chemical synthesis, which gives it several advantages compared to conventional vaccines. Although vaccination is the best preventive strategy against foot and mouth disease (and most infectious diseases), the conventional vaccines based on attenuated or inactivated viruses have many disadvantages. This is the reason for the interest in what are known as subunit vaccines, which include those based on peptides, such as the one described here.

Pompeu Fabra University, represented by Francesc Posas, the Vice-rector for Science Policy, signed an exclusivity agreement on 7 October with Virbac, a French multinational company that is a leader in the animal health sector, to market a technology developed in the Department of Experimental and Health Sciences (CEXS). It is a veterinary vaccine for the prevention of foot and mouth disease, the most economically devastating animal disease worldwide.

In this context, the exclusivity agreement with Virbac includes the production, evaluation and eventual marketing of the vaccine in the People's Republic of China, where the market for these vaccines amounts to more than 200 million dollars a year for the pig sector alone.

Friday October 25, 2013/ Universitat Pompeu Fabra/ Spain.
http://www.upf.edu

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