Creative Bioarray provides a cGMP-compliant Vero cell bank by following the industry-standard cell bank system to help our customers worldwide. By using cGMP Vero cell banking services, our clients can avoid cumbersome and time-intensive production of their cell bank and eliminate associated risks and costs. Thus, our clients can immediately start the cGMP Vero cell bank according to a fully tested manufacturing workflow.

Creative Bioarray provides a cGMP-compliant HEK293 cell bank by following the industry-standard cell bank system to help our customers worldwide. We have dedicated cell bank manufacturing scientists and quality professionals who create custom production processes for high-quality cell banks. Before cGMP manufacturing, we demonstrate key process parameters and quality attributes to our customers in a pilot or engineering.

Creative Bioarray provides a cGMP-compliant CHO cell bank by following the industry-standard cell bank system to help our customers worldwide. Our platform is equipped with cGMP production facilities, and extensive technical and regulatory expertise to support our clients' research. We also have a wealth of experience and knowledge and will advise on the most appropriate and cost-effective testing strategy to meet scientific and regulatory requirements.

Evaluating the potential side effects of human pharmaceuticals on the immune system should be incorporated into standard drug development process. Toxicity to the immune system includes inhibition or enhancement of the immune response. Inhibiting the immune response can result in a decrease in host resistance to infectious agents or tumor cells, while enhanced immune response can exacerbate autoimmune diseases or allergies. Currently, the assessment of immunotoxic effects depends on different animal models. With a few exceptions, the immune system of humans and experimental animals are very similar. Most drugs that inhibit the immune system in humans produce similar results in rodents, and the mechanisms for immunosuppressive action are similar.

High Throughput Screening (HTS) is a drug discovery process that allows automated detection of large numbers of chemical and/or biological compounds for a specific biological target. It speed up target analysis, as large scale compound libraries can be quickly screened in a cost-effective way. HTS should be seen as a fast scan of biological processes by which compounds with poor or no effects can be rapidly excluded from the analysis pipeline.

The success of any ion channel research program involves complex decisions that require specific expertise to address the complexities of these difficult biological targets. At Creative Bioarray, we have a team dedicated to helping you identify these choices, and we can work with you from determining the right detection format (binding and/or functional) and platform up to the data interpretation. From single-cell manual patch clamp (the gold standard) to high-throughput 384-well automated electrophysiological instruments, we have the capabilities to utilize platforms and strategies to deliver

Established from the surgical resection of a left parieto-occipital glioblastoma from a 47-year-old man in 1980; cells were described to secrete plasminogen activator, to be clonogenic in soft agar and to be tumorigenic in nude mice; DNA fingerprinting showed unequivocally that SNB-19 is a subclone of the astrocytoma cell line U-251 MG)

Special edition cells are isolated from the tissue types described. Cells are sterility and virus tested. All tissues used for cell isolation are obtained under informed consent. Creative Bioarray complies with the U.S. Health Insurance Portability and Accountability Act (HIPAA). Characterization standards for special edition cells have not been established.

Human Primary Tracheal Fibroblasts are isolated from normal human tracheal tissue. Human Primary Tracheal Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based coating solution for 2 min and incubated in Creative Bioarray' Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells at passage 1 are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 0.5x10^6 cells per ml.

Creative Bioarray offers expertise and services in assay development, screening, and data analysis for HCS, where the readout is based on images obtained using high-throughput microscopy systems. Our team has expertise in all areas of high content image-based screening including sample preparation, image acquisition, image analysis, image data management, and algorithm development.