Interest of the serological tests related to PCV2

Given the high prevalence of the infection due to the PCV2 and its presence in healthy and sick animals, the serological tests against this pathogen have been questioned as a diagnostic test.
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These articles on porcine circovirus associated diseases present the most novel aspects, especially from the practical point of view, on aetiology, pathogeny, epidemiology, diagnosis, treatment and prevention of PCVAD.

Given the high prevalence of the infection due to the PCV2 and its presence in healthy and sick animals, the serological tests against this pathogen have been questioned as a diagnostic test.

Available data indicate that PCV2 has the ability to modulate the immune response, not only during the obvious overt disease but also in a subclinically infection.

One issue is to overcome maternal immunity, which is true for all PCV2 vaccines in the market, and another is whether the most from these vaccines is achieved independently of the PCV2 antibody titre at vaccination

We may have some highly efficient vaccines, but we shouldn’t forget that for their application we must obtain good diagnostic information, and that in all cases we should not lose sight of good management and a good control of the concomitant diseases.

Between 1995 and 1997, at the beginning of an epizootic called “maladie de l’amagrissement du porcelet” (MAP), it was observed that the farms that were most affected and that had the most losses, generally presented obvious deviations from what we would consider to be a suitable management of the animals and facilities. This is why Dr. François Madec made a list of management practices with the aim of improving the anomalous situation observed.

Pigs that are not affected by the disease tend to have a quantity of sero-neutralizing (and also total) antibodies against PCV2, which is significantly greater than those that cause disease

The aim of this article is to discuss those differentiating topics which are relevant from a practical point of view and which in some way elude the disease's definition.